Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections. (13th July 2018)

• Record Type: Journal Article
• Authors: Khamash, Dina F; Voskertchian, Annie; Tamma, Pranita D; Akinboyo, Ibukunoluwa C; Carroll, Karen C; Milstone, Aaron M
• Is Part Of: Journal of the Pediatric Infectious Diseases Society. Volume 8:Number 4(2019)
• Page Start: 351
• Page End: 353
• Publication Date: 2018-07-13
• Subjects: antibiotic resistance -- clindamycin -- community-onset infection -- pediatrics -- Staphylococcus aureus -- trimethoprim-sulfamethoxazole; Communicable diseases in children -- Periodicals; Children -- Diseases -- Periodicals; 618.929
• DOI: 10.1093/jpids/piy062
• Languages: English
• ISSNs: 2048-7193

Abstract

Abstract: The epidemiology of Staphylococcus aureus infection in children is dynamic. We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.