Multiple peritricuspidal reentry tachycardias after cardiac infiltration by leukaemia: a case report. Issue 2 (23rd April 2019)

• Record Type: Journal Article
• Authors: Kawamura, Iwanari; Fukamizu, Seiji; Miyazawa, Satoshi; Hojo, Rintaro
• Editors: de Potter, Tom; Sommer, Philipp; Luermans, Justin; Patel, Peysh A; Camm, Fielder Christian
• Is Part Of: European heart journal. Volume 3:Issue 2(2019)
• Publication Date: 2019-04-23
• Subjects: Macro reentry -- Atrial flutter -- Rhythmia mapping system -- Leukaemia -- Infiltration -- Case report; Cardiology -- Periodicals; Cardiology -- Case studies -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Diseases -- Case studies -- Periodicals; 616.12
• DOI: 10.1093/ehjcr/ytz046
• Languages: English
• ISSNs: 2514-2119

Abstract

Abstract: Background: Cardiac involvement by malignant lymphocytic neoplasms is a rare phenomenon. Little is known concerning cardiotoxicity in the chronic phase after completion of treatment. Case summary: A 50-year-old woman with a past history of cardiac involvement of acute lymphoblastic leukaemia (ALL) underwent electrophysiologic study and catheter ablation for symptomatic atrial tachycardia (AT). She was diagnosed with ALL when she was 8 years old and treated with systematic chemotherapy with prednisolone and vincristine. After complete remission, she suffered from repeated palpitations beginning at the age of 16 years. Electrophysiologic study using high-density (HD) mapping showed two types of peritricuspid AT in addition to low voltage in the right atrium with conduction delay. Discussion: Cardiac involvement by malignant lymphocytic neoplasms is a rare phenomenon, and cardiac infiltration often disappears after remission of ALL. Thus, little is known about cardiac electrophysiological characteristics in the chronic phase of complete remission of ALL. We describe a rare case of a patient with multiple peritricuspidal reentry tachycardias after cardiac infiltration by leukaemia using a HD mapping system.