European experience of robot‐assisted kidney transplantation: minimum of 1‐year follow‐up. (25th May 2018) - Territo, Angelo
Abstract : Objectives: To evaluate functional results, graft survival and late complications in patients who underwent robot‐assisted kidney transplantation (RAKT) and who had a minimum of 1 year of follow‐up data, and to analyse the correlations between surgical data and functional results at a minimum of 1‐year postoperatively and between renal function in the immediate postoperative period and after 1 year. Materials and Methods: A common prospectively collected RAKT database was created by the European Robotic Urological Section (ERUS) RAKT working group, which included eight different European centres. In each centre RAKTs were performed with kidneys from living donors. Data on demographic variables, surgical results, graft survival, functional outcomes (creatinine and estimated glomerular filtration rate [eGFR]) on postoperative days 7 and 30 and at 1 year, and late complications were extracted from the common database. Results: A total of 147 RAKTs were performed by the ERUS RAKT working group. Of the 147 patients, 83 had at least 1‐year follow‐up (mean [range] 21 [13–27] months). Of these 83 patients, 30 were women. The patients' median (range) age was 43 (30–75) years, body mass index was 25.3 (20–40) kg/m 2, pre‐transplantation serum creatinine was 517 (198–1 414) μmol/L and estimated GFR (eGFR) was 10 (3–29) mL/min per 1.73 m 2 . Of the 83 cases, 46 were pre‐emptive. The median (range) overall ischaemia time was 116 (53–377) min. The median (range) rewarming time was 60 (35–110) min. At 1‐year follow‐up, the median (range) serum creatinine was 131 (66–244) μmol/L, with a median (range) eGFR of 57.4 (28–97) mL/min per 1.73 m 2 . There was no statistically significant difference between functional data at postoperative day 30 and those at 1 year for creatinine ( P = 0.78) or eGFR ( P = 0.91). Regarding the correlation between the surgical data and the functional outcomes, the data showed that overall operating time and rewarming time did not affect the graft function at 1 year. Three cases of graft loss occurred as a result of massive arterial thrombosis within the first postoperative week. Late complications comprised one case of ureteric stenosis and one case of graft pyelonephritis. No late vascular complications or cases of incisional hernia were recorded. Conclusion: Findings at 1‐year follow‐up indicate RAKT from a living donor to be a safe procedure in a properly selected group of recipients. RAKT was associated with a low complication rate and there was maintenance of excellent graft survival and function. This is the first and largest study to report functional results after RAKT from a living donor with a minimum follow‐up of 1 year.