Cover Feature: Differently Tagged Probes for Protein Profiling of Mitochondria (ChemBioChem 9/2019). (9th April 2019)

• Record Type: Journal Article
• Authors: Dong, Jia; Hong, Danqi; Lang, Wenjie; Huang, Jintao; Qian, Linghui; Zhu, Qing; Li, Lin; Ge, Jingyan
• Is Part Of: Chembiochem. Volume 20:Number 9(2019)
• Page Start: 1089
• Page End: 1089
• Publication Date: 2019-04-09
• Subjects: chemoproteomics -- click chemistry -- imaging agents -- mitochondrial proteins -- organelle-focused probes; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201900221
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : The cover feature picture shows a proteomics method based on probes with a cysteine reactive group, a clickable handle, and mitochondrion‐targeting moieties, including triphenlylphosphonium cations, tetraethylrhodamine, and mitochondrion‐penetrating peptides (Fx rFx K). The results showed that different groups targeted distinct proteins with partial overlap. More information can be found in the full paper by Q. Zhu, J. Ge, et al. on page 1155 in Issue 9, 2019 (DOI: 10.1002/cbic.201800735 ).