Concentric rings K‐space trajectory for hyperpolarized 13C MR spectroscopic imaging. Issue 1 (22nd December 2014)

• Record Type: Journal Article
• Authors: Jiang, Wenwen; Lustig, Michael; Larson, Peder E. Z.
• Is Part Of: Magnetic resonance in medicine. Volume 75:Issue 1(2016:Jan.)
• Page Start: 19
• Page End: 31
• Publication Date: 2014-12-22
• Subjects: hyperpolarized 13C -- spectroscopic imaging -- concentric rings -- non‐Cartesian trajectory -- parallel imaging; Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25577
• Languages: English
• ISSNs: 0740-3194

Abstract

Abstract : Purpose: To develop a robust and rapid imaging technique for hyperpolarized 13 C MR Spectroscopic Imaging and investigate its performance. Methods: A concentric rings readout trajectory with constant angular velocity is proposed for hyperpolarized 13 C spectroscopic imaging and its properties are analyzed. Quantitative analyses of design tradeoffs are presented for several imaging scenarios. The first application of concentric rings on 13 C phantoms and in vivo animal hyperpolarized 13 C MR Spectroscopic Imaging studies were performed to demonstrate the feasibility of the proposed method. Finally, a parallel imaging accelerated concentric rings study is presented. Results: The concentric rings MR Spectroscopic Imaging trajectory has the advantages of acquisition timesaving compared to echo‐planar spectroscopic imaging. It provides sufficient spectral bandwidth with relatively high efficiency compared to echo‐planar spectroscopic imaging and spiral techniques. Phantom and in vivo animal studies showed good image quality with half the scan time and reduced pulsatile flow artifacts compared to echo‐planar spectroscopic imaging. Parallel imaging accelerated concentric rings showed advantages over Cartesian sampling in g ‐factor simulations and demonstrated aliasing‐free image quality in a hyperpolarized 13 C in vivo study. Conclusion: The concentric rings trajectory is a robust and rapid imaging technique that fits very well with the speed, bandwidth, and resolution requirements of hyperpolarized 13 C MR Spectroscopic Imaging. Magn Reson Med 75:19–31, 2016. © 2015 Wiley Periodicals, Inc.