Hypochlorous acid gel technology—Its impact on postprocedure treatment and scar prevention. (30th March 2017)

• Record Type: Journal Article
• Authors: Gold, Michael H.; Andriessen, Anneke; Dayan, Steven H.; Fabi, Sabrina G.; Lorenc, Z. Paul; Henderson Berg, Meagan‐Helen
• Is Part Of: Journal of cosmetic dermatology. Volume 16:Number 2(2017:Jun.)
• Page Start: 162
• Page End: 167
• Publication Date: 2017-03-30
• Subjects: hypochlorous acid technology -- postprocedure care -- scar management; Skin -- Diseases -- Treatment -- Periodicals; Lasers in surgery -- Periodicals; Skin -- Pathophysiology -- Periodicals; Surgery, Plastic -- Periodicals; 616.5
• DOI: 10.1111/jocd.12330
• Languages: English
• ISSNs: 1473-2130

Abstract

Summary: Background: A pre‐and postprocedure regime aimed at prevention of infection, reduction of inflammation and risk of scarring, is to enable optimal outcomes. Objectives: The role of a hypochlorous acid containing spray and translucent scar gel formulation that combines modified silicon oil with hypochlorous acid, was explored for pre‐ and postprocedure treatment and scar management. Methods: For this purpose a literature review was conducted to explore the value of the technology used in pre‐and postprocedural regimes. A panel of dermatologists and plastic surgeons who practice in the United States discussed the summarized search results, taking into account their current clinical practice. A nominal group process for consensus was used, followed by online reviews of the manuscript. Results: Based on panel discussions, consensus was reached regarding clinical recommendations given for postprocedure treatment and scar management. The hypochlorous acid products are produced with electrolysis and are classified among biocidal substances. The technology has demonstrated efficacy and safety for pre‐and postprocedure use. The safety of hypochlorous solution use demonstrated to be comparable to that of standard local antiseptics. Small studies demonstrated better results with the scar gel compared to silicone gel regarding the appearance of hypertrophic and keloid scars, relief of associated pruritus and pain. Conclusions: A postprocedure regime using this technology, aimed at preventing infection, reducing inflammation, and promoting healing is proposed to have benefits over current regimes as it appears to be effective, safe, and well tolerated.