Physical activity for diabetes-related depression: A systematic review and meta-analysis. (June 2019)

• Record Type: Journal Article
• Authors: Narita, Zui; Inagawa, Takuma; Stickley, Andrew; Sugawara, Norio
• Is Part Of: Journal of psychiatric research. Volume 113(2019)
• Page Start: 100
• Page End: 107
• Publication Date: 2019-06
• Subjects: Exercise -- Depressive symptoms -- Diabetes mellitus -- Comorbidity; Psychiatry -- Periodicals; Mental Disorders -- Periodicals; Maladies mentales -- Périodiques; Psychiatry; Electronic journals; Periodicals; 616.89005
• DOI: 10.1016/j.jpsychires.2019.03.014
• Languages: English
• ISSNs: 0022-3956

Abstract

Abstract: Patients with diabetes have an increased risk of developing depression compared with non-diabetic individuals. We aimed to examine the utility of physical activity in the treatment of diabetes-related depression using a meta-analysis. Multiple databases were searched from inception to February 1, 2018. A random effects pooling model was used to examine the standardized mean difference and mean difference in the meta-analysis. A sensitivity analysis and meta-regression analyses were performed. Fourteen studies were included in a systematic review (1020 patients), while 13 were included in a meta-analysis (962 patients). Physical activity had a beneficial effect on depression as measured by Hedge's g (standardized mean difference = −0.59; 95% CI = −0.93 to −0.24). A sensitivity analysis indicated that the findings did not change in a meaningful way with the exclusion of studies with a high or unknown risk of bias in incomplete outcome data. Meta-regression analyses demonstrated that no covariate significantly influenced the main effect size. Physical activity had a significantly beneficial effect on depression as measured by the Beck Depression Inventory (mean difference = −2.90; 95% CI = −4.53 to −1.28). These findings suggest that physical activity may help ameliorate depression in patients with diabetes.