Acquired hemophilia A in chronic lymphocytic leukemia: A case report. (August 2019)

• Record Type: Journal Article
• Authors: Karakuş, Volkan; Kaya, Egemen; Dere, Yelda; Kurtoğlu, Erdal
• Is Part Of: Transfusion and apheresis science. Volume 58:Number 4(2019)
• Page Start: 447
• Page End: 448
• Publication Date: 2019-08
• Subjects: Chronic lymphocytic leukemia -- Acquired hemophilia A -- Malignant; Blood -- Transfusion -- Periodicals; Hemapheresis -- Periodicals; 615.39
• DOI: 10.1016/j.transci.2019.04.030
• Languages: English
• ISSNs: 1473-0502

Abstract

Abstract: Acquired hemophilia A, due to spontaneous autoantibody against FVIII, is a rare hemorrhagic disorder with an incidence of about 1 per million population per year. If unrecognized and untreated, it is associated with a high morbidly and mortality rate of 8–12%. Autoantibody against coagulation factor VIII neutralizes procoagulant activity. We report herein is such a rare case of acquired hemophilia in a patient with CLL.