Citric Acid/MCM‐48 Catalyzed Multicomponent Reaction: An Efficient Method for the Novel Synthesis of Quinoline Derivatives. Issue 23 (19th June 2019)

• Record Type: Journal Article
• Authors: Akpotu, Samson O.; Moodley, Brenda; Vamsi, Boddu; Ofomaja, Augustine; Maddila, Suresh; Jonnalagadda, Sreekantha B
• Is Part Of: ChemistrySelect. Volume 4:Issue 23(2019)
• Page Start: 7003
• Page End: 7009
• Publication Date: 2019-06-19
• Subjects: Green synthesis -- Heterogeneous catalyst -- MCM-48 -- One-pot reaction -- Quinolines.; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.201900907
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: A facile, efficient and suitable green approach has been designated for the one‐pot synthesis of quinoline derivatives in the presence of citric acid doped MCM‐48 (CAMCM‐48) as a heterogeneous catalyst. The prepared material was characterized by using various techniques like P‐XRD, SEM, TEM, TGA, FTIR and structural properties was determined by BET analysis. The reaction progressed efficiently under ethanol solvent system at room temperature condition to afford the corresponding products. This protocol offers many advantages such as simple synthesis, easy work‐up, short reaction times (15 min), good stability, reusability and no chromatographic separation techniques plus excellent yields (91‐98%). Abstract : An efficient quinolone derivative was synthesised by using with a recyclable citric acid doped MCM‐48 (CAMCM‐48) heterogeneous catalyst. The catalyst performed efficiently and robustly in multicomponent reaction. This protocol offers many advantages such as simple preparation, short reaction time (15 mins), easy work‐up, good stability, highly reusability and no chromatographic separation techniques plus excellent yields (91‐98%).