Central venous catheter infection in Canadian home parenteral nutrition patients: a 5-year multicenter retrospective study. (23rd April 2020)

• Record Type: Journal Article
• Authors: Saqui, Olivia; Fernandes, G.; Allard, J.
• Is Part Of: British journal of nursing. Volume 29:Number 8(2020)
• Page Start: S34
• Page End: S42
• Publication Date: 2020-04-23
• Subjects: Central venous catheter -- Home parenteral nutrition -- Bacteremia; Nursing -- Periodicals; 610.73
• DOI: 10.12968/bjon.2020.29.8.S34
• Languages: English
• ISSNs: 0966-0461

Abstract

Abstract : HIGHLIGHTS: A lower central venous catheter (CVC) infection rate suggests an improvement in practice and education. CVC infection remains a complication that often requires significant health care resources. Use of tunneled CVC and patient education on catheter care reduces CVC infection rates. Objectives: CVC infection is one of the most frequent, life-threatening complications in home parenteral nutrition (HPN) patients. Our objective was to conduct a 5-year retrospective chart review regarding CVC infections in 3 adult HPN programs. Methods: Data were collected from the Canadian HPN Registry and patient charts that include demography, infection diagnosis, blood cultures, and treatments. Results: Results are reported as median (range) ± standard error of mean or population frequency. Eighty-one charts were reviewed. Mean age was 51.98 ± 1.71 years. Short bowel syndrome (54.3%) was the primary diagnosis, with 36 months (range, 1324 months) median length of HPN therapy. Forty-seven subjects (58%) had infections over a 5-year period. Of these, there were 144 sepsis events. There was positive correlation ( r =0.423; P <0.001) between number of infections and HPN duration. The median length of time the CVC was in place was 281 (range, 14–4380) days. There were 66.7% tunneled CVCs; 25.9% peripherally inserted central catheters (PICCs), and 7.4% implanted venous port. In this sample, there was no association between line infection and catheter type. Most patients presented with fever (58.3%) and chills (38.2%). Blood cultures were done (89.6%), and coagulase negative Staphylococcus was the resulting pathogen present in 25.7%. Patients with bloodstream infection were treated for 17.9 ± 1.2 days with combination antibiotics (22.2%). Overall, the CVC infection rate was 0.97 per 1000 catheter days. Conclusion: We found the standard approach to infection prevention is comparable to reports in literature. However, a subset of patients with multiple CVC infections require education with an emphasis on preventive techniques in order to reduce the incidence of infection.