Chromanone Acid Derivatives from the Stem Bark of Calophyllum incrassatum. (January 2019)

• Record Type: Journal Article
• Authors: Hasanah, U; Tjahjandarie, T S; Tanjung, M
• Is Part Of: IOP conference series. Volume 217(2019)
• Publication Date: 2019-01
• Subjects: Calophyllum incrassatum -- Calofolic acid B -- Apetalic acid -- P-388 cells; Earth sciences -- Periodicals; Environmental sciences -- Congresses; Environmental sciences -- Periodicals; 550.5
• DOI: 10.1088/1755-1315/217/1/012010
• Languages: English
• ISSNs: 1755-1307

Abstract

Abstract: Two chromanone acid derivatives, calofolic acid B (1 ) and apetalic acid (2 ) were isolated from the stem bark of Calophyllum incrassatum . The structures of both compounds were elucidated by UV, IR, HRESIMS, 1D and 2D NMR spectroscopies and comparison of their data with literatures. Compounds 1 -2 were evaluated for their cytotoxic activity against P-388 cells, compound (1 ) showing value IC50 1.14 μg/mL.