Proposed roadmap to stepwise integration of genetics in family medicine and clinical research. Issue 1 (16th February 2013)

• Record Type: Journal Article
• Authors: Houwink, Elisa JF; Sollie, Annet W; Numans, Mattijs E; Cornel, Martina C
• Is Part Of: Clinical and translational medicine. Volume 2:Issue 1(2013)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2013-02-16
• Subjects: Genetics registration -- Family history -- Electronic patient record -- General practice/family medicine -- Clinical research; Clinical medicine -- Periodicals; Medicine, Experimental -- Periodicals; Medical innovations -- Periodicals; Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; 616.027
• DOI: 10.1186/2001-1326-2-5
• Languages: English
• ISSNs: 2001-1326

Abstract

Abstract: We propose A step‐by‐step roadmap to integrate genetics in the Electronic Patient Record in Family Medicine and clinical research. This could make urgent operationalization of readily available genetic knowledge feasible in clinical research and consequently improved medical care. Improving genomic literacy by training and education is needed first. The second step is the improvement of the possibilities to register the family history in such a way that queries can identify patients at risk. Adding codes to the ICPC chapters "A21 Personal/family history of malignancy" and "A99 Disease carrier not described further" is proposed. Multidisciplinary guidelines for referral must be unambiguous. Electronical patient records need possibilities to add (new) family history information, including links between individuals who are family members. Automatic alerts should help general practitioners to recognize patients at risk who satisfy referral criteria. We present a familial breast cancer case with a BRCA1 mutation as an example.