Alkaloids and monoterpenes from the leaves of Isatis tinctoria Linnaeus and their chemotaxonomic significance. (October 2020)

• Record Type: Journal Article
• Authors: Xu, Zhi-Yong; Xi, Yu-Fei; Zhou, Wei-Yu; Lou, Li-Li; Wang, Xiao-Bo; Huang, Xiao-Xiao; Song, Shao-Jiang
• Is Part Of: Biochemical systematics and ecology. Volume 92(2020)
• Publication Date: 2020-10
• Subjects: Isatis tinctoria Linnaeus -- Brassicaceae -- Alkaloids -- Monoterpenes -- Chemotaxonomy; Chemotaxonomy -- Periodicals; Biochemical variation -- Periodicals; Ecology -- Periodicals; Biochemistry -- Periodicals; Ecology -- Periodicals; Chimiotaxinomie -- Périodiques; Variation biochimique -- Périodiques; Écologie -- Périodiques; 578.012
• DOI: 10.1016/j.bse.2020.104089
• Languages: English
• ISSNs: 0305-1978

Abstract

Abstract: Phytochemical investigation of the leaves of Isatis tinctoria Linnaeus led to the isolation of thirty compounds, including thirteen indole alkaloids (1–13 ), seven quinazolinone alkaloids (14–20 ), two quinoline alkaloids (21–22 ), one quindoline alkaloid (23 ), one simple amide alkaloid (24 ) and six monoterpenes (25–30 ). According to spectroscopic data analysis and comparison with the previously reported literature, their structures were elucidated. Among them, six compounds (12, 13, 17, and 22 –24 ) have not been reported from the family Brassicaceae and eight compounds (3, 7, and 25 –30 ) were isolated from the genus Isatis for the first time. Furthermore, the chemotaxonomic significance of isolated compounds has also been elaborated. Highlights: Thirty compounds (1-30 ) were isolated from the leaves of Isatis tinctoria Linnaeus. Eight compounds (3, 7, and 25-30 ) were firstly obtained from the genus Isatis . Six compounds (12, 13, 17, and 22-24 ) were reported from the family Brassicaceae for the first time. The chemotaxonomic significance of the isolated compounds was discussed.