Correlation of cochlear nerve cross-sectional area and auditory performance after cochlear implantation in prelingual children with bilateral profound hearing loss. (October 2020)

• Record Type: Journal Article
• Authors: Jain, S.; Sharma, V.; Patro, S.K.; Khera, P.; Yadav, T.; Tiwari, S.; Kaushal, D.; Soni, K.; Goyal, A.
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 137(2020:Oct.)
• Publication Date: 2020-10
• Subjects: Cochlear implantation -- Cochlear nerve cross sectional area -- MRI -- Prelingual deaf -- IT-MAIS -- CAPS score; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2020.110173
• Languages: English
• ISSNs: 0165-5876

Abstract

Abstract: Objective: To assess whether cochlear nerve (CN) cross-sectional area as measured with parasagittal magnetic resonance imaging (MRI) in prelingual pediatric deaf patients correlates with auditory performance after cochlear implantation. Study design: Prospective Cohort study. Methods: Thirty-two prelingual children with bilateral profound sensorineural hearing loss (SNHL) who received unilateral cochlear implant were included in this study. Diameters of CN at Internal auditory canal (IAC) fundus and mid-point of IAC were retrospectively measured on parasagittal images of FIESTA (Fast Imaging Employing Steady-state Acquisition) sequence MRI by two independent observers. Cross-sectional areas [π (Height/2) (Width/2)] were then correlated with post-operative CAPS (Categories of Auditory Performance) and IT-MAIS (Infant-Toddler Meaningful Auditory Integration Scale) scores regularly assessed at 3 monthly intervals post device activation. Results: The cochlear nerve was identified in all the 32 patients. Mean cross-sectional areas (CSA) of cochlear nerve were 0.71 ± 0.16 mm 2 at IAC fundus and 0.73 ± 0.18 mm 2 at mid-point of IAC. The correlation value between CSA at mid-point of IAC and CAPS score at 6 months was 0.271 ( p-value - 0.140) and correlation value between CSA at mid-point of IAC and IT-MAIS score at 6 months was 0.282 ( p-value - 0.124) which were statistically not significant. Conclusion: There was no significant correlation between the cross-sectional areas of the cochlear nerve on MRI and postoperative auditory scores as measured by CAPS and IT-MAIS scores at six months from the device activation. Hence, we conclude that above an adequate diameter, which can affect the minimum required neurons, the changes in the diameter do not have significant bearing on auditory outcomes after cochlear implantation.