Prevalence of obstructive sleep apnea in children with laryngomalacia and value of polysomnography in treatment decisions. (October 2020)

• Record Type: Journal Article
• Authors: Verkest, Valérie; Verhulst, Stijn; Van Hoorenbeeck, Kim; Vanderveken, Olivier; Saldien, Vera; Boudewyns, An
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 137(2020:Oct.)
• Publication Date: 2020-10
• Subjects: Laryngomalacia -- Obstructive sleep apnea -- Polysomnography -- Stridor; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2020.110255
• Languages: English
• ISSNs: 0165-5876

Abstract

Abstract: Objectives: Children with laryngomalacia may present with obstructive sleep apnea (OSA). The role of polysomnography (PSG) in treatment decision making for laryngomalacia is not well defined. We aimed to investigate the prevalence of OSA in children with laryngomalacia and the role of PSG in treatment decision. Methods: Retrospective medical record review of children with laryngomalacia, confirmed by direct laryngoscopy, during a period of 3 years. Demographic data, presenting symptoms, severity classification, comorbidities and pre- and postoperative PSG data were retrieved and analyzed. Data are expressed as a median (25th – 75th percentile). Results: Forty-six patients were with diagnosed laryngomalacia between March 2016 and April 2019. A complete data set was available for 44 patients, 24 males and 20 females. The median age at the time of PSG was 12 weeks (6.3–29.8). Thirty-four children (77.4%) were diagnosed with concomitant OSA. A diagnosis of OSA changed the severity classification and treatment decision in 24 cases (54.5%). Twenty-three patients underwent supraglottoplasty, five patients were treated with continuous positive airway pressure (CPAP) and nine patients had both treatments. Seven patients received conservative treatment. The obstructive apnea/hypopnea index decreased from 8.9 events/hour (4.4–12.1) to 2.4 events/hour (1.5–4.4) after supraglottoplasty (p = 0.009). Conclusions: A diagnosis of OSA was established in 77.4% of patients with larygomalacia The presence of OSA may increase the severity of symptoms in laryngomalacia, leading to a transition from watchful-waiting to active intervention with CPAP therapy or supraglottoplasty. Supraglottoplasty is a safe and effective surgical procedure for laryngomalacia. When performed in the setting of laryngomalacia with concomitant OSA, it also significantly improves OSA symptomatology. Highlights: A large number of patients with laryngomalacia has OSA. PSG is useful is in the assessment and follow-up of patients with laryngomalacia. Supraglottoplasty significantly improves OSA in children with laryngomalacia.