Adhesive graphene grown on bioceramics with photothermal property. (September 2020)

• Record Type: Journal Article
• Authors: Shen, A.; Zhao, C.; Mao, L.; Wu, Y.; Zhao, B.; Lin, K.
• Is Part Of: Materials today chemistry. Volume 17(2020)
• Publication Date: 2020-09
• Subjects: 2D carbon-based material -- CVD -- Growth in situ -- Stability -- Photothermal effect; Chemistry -- Periodicals; Materials -- Research -- Periodicals; Materials science -- Periodicals; Chemistry; Materials -- Research; Electronic journals; Periodicals; 660.282
• DOI: 10.1016/j.mtchem.2020.100322
• Languages: English
• ISSNs: 2468-5194

Abstract

Abstract: Recently, graphene has been applied to modify biomaterials due to excellent physicochemical property and biocompatibility. However, some problems still exist especially the weak binding force between graphene and other biomaterials. Herein, a promising platform with photothermal property was constructed by fabricating the adhesive graphene in situ on the surface of β-tricalcium phosphate (β-Ca3 (PO4 )2, β-TCP) bioceramics using chemical vapor deposition (CVD). The result of ultrasonic cleaning treatment of graphene modified β-TCP (G-TCP) demonstrated that the prepared graphene coating could firmly modified on β-TCP due to the occurrence of carbothermal reduction on the ceramic surface to promote the nucleation and growth of graphene. G-TCP composites exhibited excellent photothermal effects when irradiated with 808 nm near-infrared laser (NIR). The photothermal effect of G-TCP composites could induce more than 90% of osteosarcoma cell (MNNG) death in vitro . These results confirmed that the graphene could be successfully fabricated in situ on the surface of β-TCP by CVD method, and exhibited high firmness and excellent photothermal performance, revealing a promising application in the photothermal therapy of bone tumors. Highlights: Graphene growing on bioceramics via CVD method without using any catalysts. The prepared graphene film adhesion strongly on the bioceramics. The prepared graphene film exhibition excellent photothermal effects.