Chemoselective RuII‐Catalyzed Synthesis of Aryl Thiocyanates and Step‐wise Double [2+2+2] Cycloadditions to 2‐Aryl Thiopyridines. Issue 29 (22nd June 2020)

• Record Type: Journal Article
• Authors: Bhatt, Divya; Kalaramna, Pratibha; Kumar, Krishn; Goswami, Avijit
• Is Part Of: European journal of organic chemistry. Issue 29(2020)
• Page Start: 4606
• Page End: 4611
• Publication Date: 2020-06-22
• Subjects: Cycloaddition -- Heterocycles -- Homogeneous catalysis -- Synthetic methods -- Ruthenium; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202000691
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : Ru II ‐catalyzed intermolecular double [2+2+2] cycloadditions of 1, 6‐diynes and alkynylthiocyanates have been developed for the synthesis of 2‐aryl thiopyridines. Aryl thiocyanates were isolated chemoselectively as a result of initial intermolecular [2+2+2] cycloaddition product. The method offers operational simplicity and is atom economical in nature. Abstract : An atom‐economical approach towards the synthesis of aryl thiocyanates has been documented employing ruthenium‐catalyzed [2+2+2] cycloaddition strategy. Sequential Ru II ‐catalyzed intermolecular [2+2+2] cycloadditions of 1, 6‐diynes and formed aryl thiocyanates resulted in the synthesis of 2‐aryl thiopyridines.