Rising Postoperative C-Reactive Protein in Congenital Diaphragmatic Hernia: Sepsis or Inflammation?. Issue 1 (March 2019)

• Record Type: Journal Article
• Authors: Mukherjee, Devdeep; Ranganna, Ranganath
• Is Part Of: Journal of neonatology. Volume 33:Issue 1/4(2019)
• Page Start: 26
• Page End: 28
• Publication Date: 2019-03
• Subjects: Newborn -- mortality in newborns -- neonatal care -- neonatal infection; Neonatology -- Periodicals; Neonatology -- India -- Periodicals; 618.9201
• DOI: 10.1177/0973217919896186
• Languages: English
• ISSNs: 0973-2179

Abstract

Abstract: This study aims to determine the incidence of sepsis in neonates operated for congenital diaphragmatic hernia and ascertain if the level or pattern of C-reactive protein (CRP) could be used to differentiate neonates with sepsis from noninfective inflammation. This study suggests that CRP patterns within the first 48-hours after surgical intervention for congenital diaphragmatic hernia could be used to differentiate neonates with noninfective inflammation from sepsis. A larger, multicentric study is needed to differentiate sepsis from inflammation on the basis of CRP rise and thereby help in avoiding unnecessary use of antibiotics.