A pilot study to evaluate urine LAM assay for diagnosis of pulmonary tuberculosis among non-HIV patients. (October 2020)

• Record Type: Journal Article
• Authors: Gupta, Akshita; Kumar, Ajay; Ashraf, Asem Ali; Madigubba, Haritha; Chawla, Kiran
• Is Part Of: Tropical doctor. Volume 50:Number 4(2020)
• Page Start: 343
• Page End: 346
• Publication Date: 2020-10
• Subjects: Point of care -- pulmonary tuberculosis -- lateral flow assay -- non-HIV; Tropical medicine -- Periodicals; Medical care -- Developing countries -- Periodicals; Developing Countries -- Periodicals; Tropical Medicine -- Periodicals; Tropische geneeskunde; 616.9883
• DOI: 10.1177/0049475520936164
• Languages: English
• ISSNs: 0049-4755

Abstract

There is a great need to improve diagnostic tools for tuberculosis where the majority are without HIV co-infection in resource-poor settings and high-burden areas such as India. The urine LAM assay has not hitherto been studied and may have a role to play. Our study found that, as a stand-alone diagnostic tool, the assay was suboptimal when compared to Xpert MTB/Rif. However, a combination of LAM assay along with sputum microscopy may be useful in settings where molecular testing is unavailable.