MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Issue 19 (28th July 2020)

• Record Type: Journal Article
• Authors: Elad, Sharon; Cheng, Karis Kin Fong; Lalla, Rajesh V.; Yarom, Noam; Hong, Catherine; Logan, Richard M.; Bowen, Joanne; Gibson, Rachel; Saunders, Deborah P.; Zadik, Yehuda; Ariyawardana, Anura; Correa, Maria Elvira; Ranna, Vinisha; Bossi, Paolo
• Other Names: Arany Praveen investigator.; Al‐Azri Abdul Rahman investigator.; Blijlevens Nicole investigator.; Hovan Allan investigator.; Fregnani Eduardo investigator.; Fulton Janet investigator.; Gueiros Luiz Alcino investigator.; Rouleau Tanya investigator.; Coller Janet K. investigator.; Al‐Dasooqi Noor investigator.; Wardill Hannah investigator.; Ameringer Suzanne investigator.; Antunes Héliton Spindola investigator.; Bateman Emma H. investigator.; Bektas Kivanc investigator.; Bensadoun René‐Jean investigator.; Ten Bohmer K. investigator.; Brito‐Dellan Norman investigator.; Castillo Daniel investigator.; Chiang Karen investigator.; de Mooij Charlotte investigator.; Eilers June investigator.; Epstein Joel investigator.; Galiti Dimitra investigator.; Fall‐Dickson Jane M. investigator.; Gobbo Margherita investigator.; Issa Hazboun Hanan investigator.; Jensen Siri Beier investigator.; Johansen Jorgen investigator.; Joy Jamie investigator.; Joy K. investigator.; Kandwal Abhishek investigator.; Kataoka Tomoko investigator.; Keefe Dorothy investigator.; Loprinzi Charles L. investigator.; Lubart Rachel investigator.; Skripnik Lucas Anna investigator.; Majorana Alessandra investigator.; Mayo Bronwen investigator.; de Mooij Charlotte investigator.; Mori Takehiko investigator.; Nair Raj G. investigator.; Nasr Narmin investigator.; Nicolatou‐Galitis Ourania investigator.; Ottaviani Giulia investigator.; Migliorati Cesar investigator.; Pentenero Monica investigator.; Porcello Lorraine investigator.; Peterson Douglas investigator.; Potting Carin investigator.; Raber‐Durlacher Judith investigator.; van Sebille Ysabella Z. A. investigator.; Soga Yoshihiko investigator.; Sonis Stephen investigator.; Stringer Andrea M. investigator.; Thorpe Daniel investigator.; Tilly Vanessa investigator.; Tissing Wim investigator.; Toro Juan J. investigator.; Treister Nathaniel Simon investigator.; Vaddi Anusha investigator.; Weikel Dianna investigator.; van de Wetering Marianne investigator.; Zur Eyal investigator.;
• Is Part Of: Cancer. Volume 126:Issue 19(2020)
• Page Start: 4423
• Page End: 4431
• Publication Date: 2020-07-28
• Subjects: cancer -- gastrointestinal -- guidelines -- mucositis -- Multinational Association of Supportive Care in Cancer and International Society for Oral Oncology (MASCC/ISOO) -- oral; Cancer -- Periodicals; Cancer -- Cytopathology -- Periodicals; 616.99405
• DOI: 10.1002/cncr.33100
• Languages: English
• ISSNs: 0008-543X

Abstract

Abstract : Background: Mucositis is a significant toxicity of cancer therapy with numerous systemic sequelae. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for the management of mucositis. Methods: The literature was reviewed systematically to identify interventions for mucositis. Studies were rated according to the presence of major and minor flaws according to previously published criteria. The body of evidence for each intervention and in each treatment setting was assigned a level of evidence based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible . Results: The guideline covers evidence from 1197 publications related to oral or gastrointestinal mucositis. Thirteen new guidelines were developed for or against the use of various interventions in specific treatment settings, and 11 previous guidelines were confirmed after aa review of new evidence. Thirteen previously established guidelines were carried over because there was no new evidence for these interventions. Conclusions: The updated MASCC/ISOO Clinical Practice Guidelines for mucositis provide professional health caregivers with a clinical setting‐specific, evidence‐based tool to help with the management of mucositis in patients who have cancer. Abstract : The Multinational Association of Supportive Care in Cancer and the International Society of Oral Oncology developed clinical practice guidelines for the management of mucositis, with the first edition published in 2004 and periodically updated. This summary presents the 2019/2020 guidelines update, which is based on a systematic review, and generates a tool that will help clinicians to select evidence‐based interventions.