Case of melorheostosis associated with ipsilateral verrucous epidermal nevus, linear connective tissue nevus, diffuse hyperpigmentation and hypertrichosis: A fortuitous coincidence?. Issue 9 (12th July 2020)

• Record Type: Journal Article
• Authors: Di Altobrando, Ambra; Neri, Iria; Gurioli, Carlotta; Misciali, Cosimo; Baraldi, Carlotta; Pedrini, Elena; Gnoli, Maria; Tremosini, Morena; Sangiorgi, Luca; Patrizi, Annalisa
• Is Part Of: Journal of dermatology. Volume 47:Issue 9(2020)
• Page Start: 1063
• Page End: 1066
• Publication Date: 2020-07-12
• Subjects: connective tissue nevus -- hyperpigmentation -- hypertrichosis -- melorheostosis -- verrucous epidermal nevus; Dermatology -- Periodicals; Dermatology -- Japan -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1111/1346-8138.15460
• Languages: English
• ISSNs: 0385-2407

Abstract

Abstract : Melorheostosis (MEL) is a rare benign bone disorder that can be associated with several anomalies, including vascular abnormalities, nevus sebaceus, unilateral nevoid telangiectasia, linear scleroderma and hypertrichosis. We report the case of a 6‐year‐old patient who showed an unusual co‐occurrence of bone hyperostosis and different skin lesions affecting the same side of the body: MEL, verrucous epidermal nevus, connective tissue nevus, linear scleroderma‐like disorder, hyperpigmentation and hypertrichosis. The spatial co‐occurrence of these conditions made us speculate as to whether they originated from a common genetic mechanism or if their co‐occurrence was completely accidental.