Front Cover Picture: HFIP‐Mediated Decarboxylative [4+3]‐Annulation of Azaoxyallyl Cations with Isatoic Anhydride (Adv. Synth. Catal. 17/2020). Issue 17 (21st July 2020)

• Record Type: Journal Article
• Authors: Kim, Eunjin; Lee, Chang Yoon; Kim, Sung‐Gon
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 17(2020)
• Page Start: 3447
• Page End: 3447
• Publication Date: 2020-07-21
• Subjects: Benzodiazepinedione -- Annulation -- Decarboxylative addition -- Azaoxyallyl cation -- Isatoic anhydride; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202000800
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract : The front cover picture, provided by Sung‐Gon Kim and his co‐workers, illustrates an efficient [4+3]‐annulation reaction between in situ generated azaoxyallyl cations and isatoic anhydride to afford seven‐membered 1, 4‐benzodiazepinediones. This annulation involves the cascade reaction of decarboxylative addition of hexafluoroisopropanol (HFIP) to isatoic anhydride, addition to the azaoxyallyl cation generated from α‐halohydroxamate, and intramolecular substitution to yield 1, 4‐benzodiazepinediones. Details of this work can be found in the full paper on pages 3594–3603 (E. Kim, C. Y. Lee, S.‐G. Kim, Adv. Synth. Catal . 2020, 362, 3594–3603; DOI: 10.1002/adsc.202000439 ).