What's Hot, What's Not: The Trends of the Past 20 Years in the Chemistry of Odorants. Issue 38 (20th July 2020)

• Record Type: Journal Article
• Authors: Armanino, Nicolas; Charpentier, Julie; Flachsmann, Felix; Goeke, Andreas; Liniger, Marc; Kraft, Philip
• Is Part Of: Angewandte Chemie international edition. Volume 59:Issue 38(2020)
• Page Start: 16310
• Page End: 16344
• Publication Date: 2020-07-20
• Subjects: fragrances -- odorants -- olfactory properties -- sustainability -- terpenoids; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202005719
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: This review is the sequel to the 2000 report on the recent advances in the chemistry of odorants and it summarizes the developments in fragrance chemistry over the past 20 years. Following the olfactory spectrum set out in that report, trendsetting so‐called captive odorants (patent‐protected ingredients unavailable to the market) are presented according to the main odor families: "fruity", "marine", "green", "floral", "spicy", "woody", "amber", and "musky". The design of odorants, their chemical synthesis, and their use in modern perfumery are illustrated with prominent examples. Featured are new fruity odorants that provide signature in the top note, as well as precursor technology. In the green domain, focus is on leafy notes and green pear. New benzodioxepines and benzodioxoles have modernized the marine family and required a revision of the existing olfactophore models. The replacement of Lilial and Lyral kept the industry busy in the floral domain with a plethora of new "muguets". There was continued activity in the domain of rose odorants, especially in the area of rose ketones. Biotechnology became significant, for example, with Clearwood and Ambrofix, and the principal odorants of vetiver oil in the woody family have been found. Fourth and fifth families of musk odorants were also discovered and populated. Thus, new avenues for further explorations into fragrance chemistry have been opened. Abstract : Around the world in 80 scents : Take a bite of fruity Tropicalia, explore the lush greeneries of Bamboo Ketone and dive into the clear waters of Azurone. Stroll through blossoming Nympheal fields and let yourself be carried away with comforting odors from renewable sources, such as rotundone, β‐santalol and Ambrocenide. A report on the past 20 years in the molecular world of odors.