Multicentric adrenocorticotropic hormone -producing steroid cell tumor of the fallopian tube & broad ligament in a 15 year old girl. (1st September 2020)

• Record Type: Journal Article
• Authors: Hamdy, Omar; Saleh, Gehad A.; Eldegwi, Sara A.; Elsayed, Mohammed; Metwally, Islam H.; Naguib, Reham; Setit, Ahmed
• Is Part Of: Gynecological endocrinology. Volume 36:Number 9(2020)
• Page Start: 835
• Page End: 838
• Publication Date: 2020-09-01
• Subjects: Virilism -- amenorrhea -- fallopian tube neoplasms -- cushing; Endocrine gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1
• DOI: 10.1080/09513590.2020.1731451
• Languages: English
• ISSNs: 0951-3590

Abstract

Abstract: Steroid cell tumors occur usually in the ovaries with very few reported cases of extra-ovarian origin. Our patient was a fifteen year old female, complaining from secondary amenorrhea and voice deepening. Values of serum cortisol, DHEA, FSH & LH were normal. Serum Testosterone was elevated while ACTH-pm was markedly elevated. MRI described bilateral solid para-ovarian masses. Exploration revealed two bilateral tubal extraluminal cysts & a right broad ligament cyst which were all excised. Pathological examination led to the diagnosis of steroid cell tumor. Serum testosterone & ACTH returned to normal levels after surgery with subsequent regression of the virilizing symptoms. We can conclude that extra-ovarian steroid cell tumors are extremely rare. They are usually presented with virilizing symptoms and hormonal abnormalities. Surgery is the main line of treatment.