Foveal photoreceptors loss and then recovery after treatment in a chronic myelogenous leukemia patient. (17th August 2020)

• Record Type: Journal Article
• Authors: Hsia, Ning-Yi; Lin, Chun-Ju; Lin, Hui-Ju; Wu, Kang-Hsi
• Is Part Of: Pediatric hematology and oncology. Volume 37:Number 6(2020)
• Page Start: 545
• Page End: 548
• Publication Date: 2020-08-17
• Subjects: Chronic myelogenous leukemia -- pediatric -- retina; Pediatric hematology -- Periodicals; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Hematologic Diseases -- Child; Hematologic Diseases -- Infant; Neoplasms -- Child; 618.9215
• DOI: 10.1080/08880018.2020.1760408
• Languages: English
• ISSNs: 0888-0018

Abstract

Abstract: We report a 10-year-old boy with chronic myelogenous leukemia (CML)-related retinopathy of the eyes. Foveal photoreceptors loss was noted in the right eye, but it was restored with a continued ellipsoid zone after systemic 6-week imatinib mesylate and hydroxyurea treatment. Spectral-domain optical coherence tomography images of the foveal photoreceptors change in the right eye were taken. His best-corrected visual acuity of the right eye recovered from 20/100 to 20/20. Prompt treatment of the underlying CML could result in improvement or resolution of the ocular findings, and even foveal photoreceptors loss might be reversible with good visual acuity recovery.