Carpal tunnel syndrome in paediatric patients: A novel association with Kosaki overgrowth syndrome. (September 2020)

• Record Type: Journal Article
• Authors: Walker, Harriet; Foster, Alison; Cole, Trevor; Jester, Andrea
• Is Part Of: JPRAS open. Volume 25(2020)
• Page Start: 83
• Page End: 87
• Publication Date: 2020-09
• Subjects: Kosaki overgrowth syndrome -- KOGS -- Carpal tunnel syndrome -- Paediatric carpal tunnel syndrome; Surgery, Plastic -- Great Britain -- Periodicals; 617.9505
• DOI: 10.1016/j.jpra.2020.07.001
• Languages: English
• ISSNs: 2352-5878

Abstract

Summary: Carpal tunnel syndrome in a paediatric population is vanishingly rare and usually associated with lysosomal storage disorders such as mucopolysaccharidosis (MPS). Overgrowth syndromes similarly are rare and are characterised by increased skeletal growth alongside typical dysmorphic features and intellectual delay and as such the acronym OGID (overgrowth intellectual delay) is now widely used. Kosaki overgrowth syndrome (KOGS) is a newly recognised OGID with only 6 cases to date reported in the literature. Here we report a 7th case of KOGS with a new finding of carpal tunnel syndrome not previously described. We discuss similarities between the intraoperative findings during carpal tunnel decompression with findings seen in patients with MPS.