Chemical constituents from the bark of bauhinia purpurea and their NO inhibitory activities. Issue 17 (1st September 2020)

• Record Type: Journal Article
• Authors: Ni, Lin; Huang, Wei; Shi, Yan; Wang, Heshan; Qiu, Yatie; Xu, Huiyou
• Is Part Of: Natural product research. Volume 34:Issue 17(2020)
• Page Start: 2424
• Page End: 2429
• Publication Date: 2020-09-01
• Subjects: Bauhinia purpurea -- phenylpropanoid glucoside -- norsesquiterpene -- X-ray -- NO inhibition; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1543672
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Phytochemical studies led to the isolation of a new phenylpropanoid glucoside, named purpuroside (1 ), along with eight known compounds (2–9 ) from the bark of Bauhinia purpurea . The structure of the new compound was elucidated on the basis of its spectroscopic data. The absolute configuration of compound 2 was verified by X-ray diffraction analysis. Compounds 1, 2, 7, 8, and 9 inhibited NO production in mouse peritoneal macrophages with IC50 values from 35.5 to 63.0 μ M. Abstract :