On the antioxidant activity of eumelanin biopigments: a quantitative comparison between free radical scavenging and redox properties. Issue 17 (1st September 2020)

• Record Type: Journal Article
• Authors: Cecchi, Teresa; Pezzella, Alessandro; Di Mauro, Eduardo; Cestola, Samuel; Ginsburg, David; Luzi, Mattia; Rigucci, Alessandro; Santato, Clara
• Is Part Of: Natural product research. Volume 34:Issue 17(2020)
• Page Start: 2465
• Page End: 2473
• Publication Date: 2020-09-01
• Subjects: Eumelanin -- biopigment -- DHI (5, 6‐dihydroxyindole) -- DHICA (5, 6‐dihydroxyindole-2‐carboxylic acid) -- Sepia ink -- Briggs-Rauscher assay -- Folin Ciocalteu assay; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1542391
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: The antioxidant activity of eumelanin, a ubiquitous pigment in flora and fauna, constitutes one of its most fascinating physicochemical properties. To shed light on free radical scavenging vs redox facets of such activity, we applied hydrogen atom transfer- and electron transfer-based assays to pristine Sepia ink, eumelanin from Sepia ink, chemically controlled eumelanins and their precursor building blocks. Our work contributes to the rational use of the antioxidant properties of eumelanin for health, cosmetics and environmental applications. Graphical Abstract: