Engineering a NO‐Regulated Nanofluidic Sensor through the Cyclization Reaction Strategy. Issue 49 (28th July 2020)

• Record Type: Journal Article
• Authors: Han, Yunfeng; Sun, Zhongyue; Sun, Ziyan; Chen, Xiaoya; Zhang, Yongxue; Sun, Yao; Li, Haibing
• Is Part Of: Chemistry. Volume 26:Issue 49(2020)
• Page Start: 11099
• Page End: 11103
• Publication Date: 2020-07-28
• Subjects: cyclization reactions -- ion rectification -- nanochannel -- nanosensors -- nitic oxide; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202001089
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Nitric oxide (NO) is known to be a secondary in vivo signaling agent, demonstrating various biological functions through regulating ion flux in channels. Considering the crucial role of NO in vivo, herein, a biomimetic NO‐regulated nanofluidic sensor has been fabricated through a cyclization reaction strategy. This nanofluidic sensor exhibited a promising NO selectivity, sensitivity, and non‐interference performance in complex matrices. Thus, such a NO‐driven nanosensor will be meaningful for scientific researchers to grasp the in vivo functions of NO. Abstract : NO ON–OFF : A biomimetic NO‐driven nanofluidic sensor was fabricated through a cyclization reaction strategy and exhibited high selectivity, sensitivity, and non‐interference performance in complex matrices for NO. This NO‐driven device may have wide applications for NO nanosensors