Chirality-pure carbon nanotubes show distinct complexation with recognition DNA sequences. (15th October 2020)

• Record Type: Journal Article
• Authors: Xhyliu, Fjorela; Ao, Geyou
• Is Part Of: Carbon. Volume 167(2020)
• Page Start: 601
• Page End: 608
• Publication Date: 2020-10-15
• Subjects: Carbon -- Periodicals; Carbone -- Périodiques; Koolstof; Toepassingen; Electronic journals; 546.681
• DOI: 10.1016/j.carbon.2020.06.040
• Languages: English
• ISSNs: 0008-6223

Abstract

Abstract: Pure-chirality single-wall carbon nanotubes (SWCNTs) that are non-covalently complexed with recognition DNA sequences exhibit unique interaction behavior and hybrid stability in aqueous environments. The complexation of DNA-wrapped SWCNTs was found to be a strong function of both the DNA sequence and SWCNT chiral structure, highlighted by the distinct coating displacement of the same recognition DNA sequence from a pair of (6, 5) enantiomers by a strong surfactant. A broad range of changes were observed for different DNA/SWCNT recognition pairs with surfactant exchange including the increase in nanotube photoluminescence intensity in the near-infrared (NIR) from 1.3 to 14.7-fold and time constants deduced from DNA displacement kinetics ranging from 9 s to 230 s. A large time constant of 230 s and a relatively small 4.4-fold increase in NIR emission intensity were obtained for the CTC3 TC-(7, 6) hybrid highlighting the vast potential of short DNA sequences for improved nanotube sorting and hybrid stability in aqueous environments. Additionally, CTC3 TC-(7, 6) was identified as the only hybrid to exhibit an increase in NIR fluorescence intensity in serum-containing cell culture media among all samples tested. Our results demonstrated unique optical properties and hybrid stability of DNA/SWCNT recognition pairs, providing a foundation for developing applications of chirality-pure SWCNTs. Graphical abstract: Image 1