The performance of non-ECG gated chest CT for cardiac assessment – The cardiac pathologies in chest CT (CaPaCT) study. Issue 130 (September 2020)

• Record Type: Journal Article
• Authors: Eijsvoogel, N.G.; Hendriks, B.M.F.; Martens, B.; Gerretsen, S.C.; Gommers, S.; van Kuijk, S.M.J.; Mihl, C.; Wildberger, J.E.; Das, M.
• Is Part Of: European journal of radiology. Issue 130(2020)
• Publication Date: 2020-09
• Subjects: CAD Coronary artery disease -- CAD-RADS coronary artery disease reporting and data system -- CM contrast media -- CNR contrast-to-noise ratio -- CT computed tomography -- CVE cardiovascular event -- Cx circumflex artery -- EPD electronic patient dossier -- LAD left anterior descending artery -- LM left main artery -- RCA right coronary artery -- ROI region of interest -- SNR signal-to-noise ratio; Computed tomography angiography -- Atherosclerosis -- Coronary -- Cardiac diseases -- Incidental findings; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2020.109151
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: The majority of standard non-ECG gated chest CT scans showed coronary calcification. Dedicated cardiac analysis was feasible in almost half of scans. A considerable amount of incidental cardiac findings were found. Radiologists should assess the heart on chest CTs with sufficient image quality. The CAD-RADS may provide guidance in terms of cardiovascular risk assessment. Abstract: Purpose: Evaluating the prevalence of CAD on non-ECG gated chest CTs, image quality (IQ) and the clinical performance of the CAD-RADS classification for predicting cardiovascular events (CVE). Methods: 215 consecutive patients referred for chest CTs between May 2016 and March 2018 were included (3rd-generation DSCT) using non-ECG gated acquisitions with automated tube voltage selection (110kVqual.ref /40mAsqual.ref ), pitch 2.65–3.0 and individualized contrast media injection protocols. Dedicated cardiac post-processing reconstructions (0.6 mm/0.4 mm/Kernel Bv36) were added to standard chest reconstructions. Two independent cardiac radiologists performed a 3-step analysis. In case of discrepancy, a third reader gave the final decision. Step 1: visual presence of calcifications; 2: scans with calcifications assessed for IQ using a 5-point Likert scale (poor/sufficient/moderate/good/excellent); 3: stenosis severity was analysed in detail (if Likert sufficient-excellent using CAD-RADS). Electronic patient files were checked to see if pathology was previously mentioned (incidental) and whether patients developed an CVE during follow-up. Results: 1: Calcifications were present in 156/215 cases (72.6 %), 74 of these were incidental. 2: In 68/156 (43.6 %) patients with calcifications IQ was rated sufficient-excellent. 3: CAD-RADS≥3 was seen in 39/68 patients (57.4 %), 12 times (30.8 %) findings were incidental. During follow-up (median 16 [0–35] months), 7/39 (18 %) patients with CAD-RADS≥3 developed a CVE. 17 patients died during follow-up. Conclusion: Coronary calcification on non ECG-gated chest CTs was detected in 72.6 % of patients, cardiac assessment was feasible in nearly half of these patients. Only patients with a CAD-RADS≥3 developed CVE, therefore the CAD-RADS may help identify and guide patients at risk of future CVE.