Pediatric kidney transplantation in Egypt: Results of 10‐year single‐center experience. (10th May 2020)

• Record Type: Journal Article
• Authors: Fadel, Fatina I.; Bazaraa, Hafez M.; Badawy, Hesham; Morsi, Hany A.; Saadi, Gamal; Abdel Mawla, Mohamed A.; Salem, Amr Mohamed; Abd Alazem, Eman Abobakr; Helmy, Rasha; Fathallah, Mohamed Gamal; Ramadan, Yasmin; Fahmy, Yosra Aboelnaga; Sayed, Shaimaa; Eryan, Eman Fathy; Atia, Fatma Mohammad; ElGhonimy, Mohamed; Shoukry, Ahmed I.; Shouman, Ahmed M.; Ghonima, Waleed; Salah Eldin, Mohamed; Soaida, Sherif M.; Ismail, Wesam; Salah, Doaa M.
• Is Part Of: Pediatric transplantation. Volume 24:Number 6(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-05-10
• Subjects: immunosuppressive therapy -- infection -- rejection -- renal replacement therapy -- transplantation outcome; Transplantation of organs, tissues, etc. in children -- Periodicals; 617.95408305
• DOI: 10.1111/petr.13724
• Languages: English
• ISSNs: 1397-3142

Abstract

Abstract: Pediatric kidney transplantation is a multidisciplinary therapy that needs special consideration and experience. In this study, we aimed to present CUCH experience; over a 10‐year period, as a specialized center of kidney transplantation in children. We studied 148 transplantations performed at a single center from 2009 to 2018. Pretransplant and follow‐up data were collected and graft/patient survival rates were evaluated. A total of 48 patients developed at least one rejection episode during 688 patient‐years of follow‐up. Infections, recurrence of original disease, and malignancy were the most important encountered medical complications (20%, 2%, and 1.4%, respectively). One‐year patient survival was 94.1%, while graft and patient survival was 91.9%. Graft/patient survival at 5, 7, and 9 years was 90%, 77%, and 58%, respectively. Infections were the main cause (69%) of mortality. Death with a functioning graft and CR were the main causes of graft loss (48% and 33%, respectively). Pediatric kidney transplantation in Egypt is still a challenging yet successful experience. Rejections and infections are the most frequent complications. Short‐term outcomes surpass long‐term ones and graft survival rates are similar to the international standard.