Clozapine treatment in schizophrenia, intellectual difficulty and trisomy 5p. Issue 3 (24th August 2020)

• Record Type: Journal Article
• Authors: Majothi, Naeema; Lee, Hean Yeung; Narayan, Manoj; Butterfield, Victoria
• Is Part Of: Progress in neurology and psychiatry. Volume 24:Issue 3(2020)
• Page Start: 16
• Page End: 19
• Publication Date: 2020-08-24
• Subjects: Neurology -- Periodicals; Psychiatry -- Periodicals; Nervous system -- Periodicals; 616.805
• DOI: 10.1002/pnp.673
• Languages: English
• ISSNs: 1367-7543

Abstract

Abstract : There is a considerable paucity of empirical data on the use of clozapine in people with intellectual disability, and to the authors' knowledge these are the first published data on its use in a patient with trisomy 5p and with a diagnosis of schizophrenia. In this case we describe a patient with learning difficulties and a diagnosis of trisomy 5p and schizophrenia that has responded remarkably to clozapine treatment despite numerous additional clinical risk factors.