Selective strain-promoted azide–alkyne cycloadditions through transient protection of bicyclo[6.1.0]nonynes with silver or gold. Issue 68 (27th July 2020)

• Record Type: Journal Article
• Authors: Adachi, Keisuke; Meguro, Tomohiro; Sakata, Yuki; Igawa, Kazunobu; Tomooka, Katsuhiko; Hosoya, Takamitsu; Yoshida, Suguru
• Is Part Of: Chemical communications. Volume 56:Issue 68(2020)
• Page Start: 9823
• Page End: 9826
• Publication Date: 2020-07-27
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc04606j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Complexation of bicyclo[6.1.0]nonynes (BCNs) with silver or gold results in protection from a click reaction with azides. The protection enables selective strain-promoted azide–alkyne cycloadditions of diynes keeping the BCN moiety unreacted. Abstract : Complexation of bicyclo[6.1.0]nonynes with a cationic silver or gold salt results in protection from a click reaction with azides. The cycloalkyne protection using the silver or gold salt enables selective strain-promoted azide–alkyne cycloadditions of diynes keeping the bicyclo[6.1.0]nonyne moiety unreacted.