Buoyancy-driven step emulsification on pneumatic centrifugal microfluidic platforms. Issue 17 (26th June 2020)

• Record Type: Journal Article
• Authors: Clime, Liviu; Malic, Lidija; Daoud, Jamal; Lukic, Luke; Geissler, Matthias; Veres, Teodor
• Is Part Of: Lab on a chip. Volume 20:Issue 17(2020)
• Page Start: 3091
• Page End: 3095
• Publication Date: 2020-06-26
• Subjects: Miniature electronic equipment -- Periodicals; Combinatorial chemistry -- Periodicals; Biotechnology -- Periodicals; 543.0813
• DOI: 10.1039/d0lc00333f
• Languages: English
• ISSNs: 1473-0197

Abstract

Abstract : We present here a new method for controlling the droplet size in step emulsification processes on a centrifugal microfluidic platform, which, in addition to the centrifugal force, uses pneumatic actuation for fluid displacement. Abstract : We present here a new method for controlling the droplet size in step emulsification processes on a centrifugal microfluidic platform, which, in addition to the centrifugal force, uses pneumatic actuation for fluid displacement. We highlight the importance of the interplay between buoyancy effects and the flow rate at the step junction, and provide a simple analytical model relating these two quantities to the size of the droplets. Numerical models as well as experiments with water-in-oil emulsions are performed in support of the proposed model.