A general method for cultivating single crystals from melt microdroplets. Issue 69 (24th July 2020)

• Record Type: Journal Article
• Authors: Ou, Xiao; Li, Xizhen; Rong, Haowei; Yu, Lian; Lu, Ming
• Is Part Of: Chemical communications. Volume 56:Issue 69(2020)
• Page Start: 9950
• Page End: 9953
• Publication Date: 2020-07-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc03157g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Here, we report a general strategy for rapidly cultivating single crystals from melt microdroplets within tens of minutes at the microgram scale. Abstract : The cultivation of single crystals from solution is usually a time-consuming trial-and-error process. Here, we report a general strategy for rapidly cultivating single crystals from melt microdroplets within tens of minutes at the microgram scale. This strategy was successfully applied to the important polymorphic system griseofulvin to provide missing structural information of Form III, for which single crystals could not be cultivated from solution, as well as to twenty clinical drugs to verify its generality.