Natural-abundance 17O NMR spectroscopy of magnetically aligned lipid nanodiscs. Issue 69 (29th July 2020)

• Record Type: Journal Article
• Authors: Ravula, Thirupathi; Sahoo, Bikash R.; Dai, Xiaofeng; Ramamoorthy, Ayyalusamy
• Is Part Of: Chemical communications. Volume 56:Issue 69(2020)
• Page Start: 9998
• Page End: 10001
• Publication Date: 2020-07-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc04011h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Measurement of ordering of water molecules in magnetically aligned polymer-nanodiscs using an integrated 17 O NMR and MD simulation. Abstract : Natural-abundance 17 O NMR experiments are used to investigate the hydrated water in magnetically aligned synthetic polymer based lipid-nanodiscs. Residual quadrupole couplings (RQCs) measured from the observed five 17 O (central and satellite) transitions, and molecular dynamics simulations, are used to probe the ordering of water molecules across the lipid bilayer.