Drug‐Delivery Systems: Tubulin‐Based Nanotubes as Delivery Platform for Microtubule‐Targeting Agents (Adv. Mater. 33/2020). Issue 33 (18th August 2020)

• Record Type: Journal Article
• Authors: Kim, Jinjoo; Lee, Juncheol; Lee, Jimin; Keum, Hyeongseop; Kim, Yumi; Kim, Yujin; Yu, Byeongjun; Lee, Sang Yeop; Tanaka, Junichi; Jon, Sangyong; Choi, Myung Chul
• Is Part Of: Advanced materials. Volume 32:Issue 33(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-08-18
• Subjects: anticancer therapy -- drug delivery -- microtubule‐targeting agents -- nanomedicine -- tubulin nanotubes; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.202070244
• Languages: English
• ISSNs: 0935-9648

Abstract

Abstract : In article number 2002902, Sangyong Jon, Myung Chul Choi, and co‐workers develop tubulin‐based nanotubes (TNTs) as a delivery platform for microtubule‐targeting agents with a strategy of using a target protein as a carrier. Three types of TNT structures—ring TNTs (RTNTs), single‐walled TNTs (SWTNTs), and double‐walled TNT (DWTNTs)—can be used to deliver a variety of anticancer drugs to cellular microtubules in cancer cells.