Synthesis of oxalamides by acceptorless dehydrogenative coupling of ethylene glycol and amines and the reverse hydrogenation catalyzed by ruthenium. Issue 27 (29th June 2020)

• Record Type: Journal Article
• Authors: Zou, You-Quan; Zhou, Quan-Quan; Diskin-Posner, Yael; Ben-David, Yehoshoa; Milstein, David
• Is Part Of: Chemical science. Volume 11:Issue 27(2020)
• Page Start: 7188
• Page End: 7193
• Publication Date: 2020-06-29
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d0sc02065f
• Languages: English
• ISSNs: 2041-6520

Abstract

Abstract : Ruthenium catalyzed acceptorless dehydrogenative coupling of ethylene glycol and amines to oxalamides is reported. The reverse hydrogenation reaction is also accomplished. Abstract : A sustainable, new synthesis of oxalamides, by acceptorless dehydrogenative coupling of ethylene glycol with amines, generating H2, homogeneously catalyzed by a ruthenium pincer complex, is presented. The reverse hydrogenation reaction is also accomplished using the same catalyst. A plausible reaction mechanism is proposed based on stoichiometric reactions, NMR studies, X-ray crystallography as well as observation of plausible intermediates.