Evaluation of quality of life, body image and surgical outcomes of robotic total laparoscopic hysterectomy and sentinel lymph node mapping in low‐risk endometrial cancer patients – A Robotic Gyne Club study. (3rd April 2020)

• Record Type: Journal Article
• Authors: Mereu, Liliana; Berlanda, Valeria; Surico, Daniela; Gardella, Barbara; Pertile, Riccardo; Spinillo, Arsenio; Tateo, Saverio
• Is Part Of: Acta obstetricia et gynecologica Scandinavica. Volume 99:Number 9(2020)
• Page Start: 1238
• Page End: 1245
• Publication Date: 2020-04-03
• Subjects: endometrial cancer -- quality of life -- robotic surgery -- sentinel lymph node -- single‐site robotic surgery; Gynecology -- Periodicals; Pregnancy -- Periodicals; Obstetrics -- Periodicals; 618.05
• DOI: 10.1111/aogs.13844
• Languages: English
• ISSNs: 0001-6349

Abstract

Abstract: Introduction: The aims of the study were to evaluate quality of life, cosmetic results and surgical outcomes of robotic single‐site and robotic multiport total laparoscopic hysterectomy with sentinel lymph node mapping in women treated for low‐risk endometrial cancer. Material and methods: The study is a prospective, multicenter, case‐control study conducted at Ospedale Santa Chiara in Trento and Novara and Pavia University Hospitals. Seventy‐six consecutive patients with a biopsy‐confirmed diagnosis of low‐risk endometrial cancer or atypical endometrial hyperplasia who between January 2017 and January 2019 had undergone robotic total laparoscopic hysterectomy and sentinel lymph node mapping were included. Data on surgical outcomes, quality of life and cosmetic results were prospectively collected and analyzed based on the surgical approach with robotic single‐site vs robotic multiport assistance. Patients' clinical characteristics, intra‐operative parameters, sentinel lymph node mapping results and postoperative findings were prospectively recorded. Clinical follow up was performed 4 weeks and 6 and 12 months after surgery. Fifty‐one patients underwent a robotic multiport procedure and 25 patients a robotic single‐site surgery. Results: There was one significant difference between the two groups in terms of patient characteristics: mean body mass index (BMI) in the multiport group was 29 kg/m 2 vs 24.8 kg/m 2 in the single‐site group ( P value <.001). After univariate and multivariate analysis on intraoperative and postoperative findings, a shorter surgical time was observed in the single‐site cohort than in the multiport group (148.7 vs 158.2 minutes, P value .0182). BMI also had a significant effect on surgical time ( P = .022). No differences were seen in terms of sentinel lymph node detection: the bilateral detection rate was 96.1% for multiport (66.7% bilateral, 29.4% monolateral) and 96% for single‐site (76% bilateral, 20% monolateral) procedures. No differences between the two approaches were identified with regard to postoperative complications, pain, cosmetic results or quality of life comparisons. Conclusions: For the treatment of low‐risk endometrial cancer and atypical endometrial hyperplasia with total hysterectomy and sentinel lymph node mapping, the robotic single‐port approach is comparable to the multiport procedure in terms of intraoperative and postoperative findings, and has an advantage in terms of shorter surgical times. Further studies are required to identify possible differences in quality of life and cosmetic results.