Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy. Issue 34 (26th March 2020)
- Record Type:
- Journal Article
- Title:
- Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy. Issue 34 (26th March 2020)
- Main Title:
- Solid-phase synthesis of DNA-encoded libraries via an "aldehyde explosion" strategy
- Authors:
- Paciaroni, Nicholas G.
Ndungu, John M.
Kodadek, Thomas - Abstract:
- Abstract : DNA-compatible conditions are reported for the on-resin transformation of aromatic aldehydes into many different functional groups. Abstract : We report chemistry suitable for the solid-phase synthesis of DNA-encoded libraries with an unusually high level of structural diversity. The strategy involves "exploding" an immobilized aldehyde into a plethora of different functional groups under DNA-compatible conditions.
- Is Part Of:
- Chemical communications. Volume 56:Issue 34(2020)
- Journal:
- Chemical communications
- Issue:
- Volume 56:Issue 34(2020)
- Issue Display:
- Volume 56, Issue 34 (2020)
- Year:
- 2020
- Volume:
- 56
- Issue:
- 34
- Issue Sort Value:
- 2020-0056-0034-0000
- Page Start:
- 4656
- Page End:
- 4659
- Publication Date:
- 2020-03-26
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0cc01474e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 13869.xml