Reward (BIS/BAS) mechanisms and fatigue in patients on chronic hemodialysis. Issue 6 (2nd July 2020)

• Record Type: Journal Article
• Authors: Bossola, Maurizio; Angioletti, Laura; Di Stasio, Enrico; Vulpio, Carlo; De Filippis, Daniela; Balconi, Michela
• Is Part Of: Psychology, health & medicine. Volume 25:Issue 6(2020)
• Page Start: 710
• Page End: 718
• Publication Date: 2020-07-02
• Subjects: Fatigue -- end-stage renal failure -- chronic hemodialysis treatment -- reward mechanisms -- behavioral inhibition/activation systems; Medicine and psychology -- Periodicals; Clinical health psychology -- Periodicals; 610
• DOI: 10.1080/13548506.2019.1653477
• Languages: English
• ISSNs: 1354-8506

Abstract

ABSTRACT: Recently, it has been demonstrated that chronic inflammation could have a role on fatigue onset in chronic hemodialysis (HD). Research on neuro-immune interactions highlighted that an alteration of basal ganglia functioning, secondary to chronic inflammation, may translate in a reduced motivation and altered reward processes in chronic diseases. This study investigated a possible correlation between fatigue severity and reward mechanisms, that regulate motivational dispositions, in HD patients. Evaluation scales were administered to ninety-four patients on HD (54 Male, 40 Female; Mdage = 67±26.5; Dialytic Mdage in years = 4±6.3. Fatigue was assessed by using Fatigue Severity Scale (FSS). Behavioural Inhibition System (BIS) and Behavioural Activation System (BAS) Scale was administered to investigate approach/avoidance behaviours. Anxiety and depression were measured by State-Trait Anxiety Inventory (STAI-Y) and Beck Depression Inventory (BDI-II). Results show that the distribution of HD patients for FSS score did not show a normal pattern. FSS score was significantly higher in patients with high BIS Z-score than in patients with low and medium BIS Z-score. BDI score and STAI-Y scores were similar among BIS Z-score groups of patients. Findings suggest that in patients on chronic hemodialysis there is a correlation between fatigue severity symptoms and motivational disposition mechanisms that predispose to action inhibition.