Coumarin-based fluorescent probe for the rapid detection of peroxynitrite 'AND' biological thiols. Issue 23 (3rd April 2020)

• Record Type: Journal Article
• Authors: Wu, Luling; Tian, Xue; Groleau, Robin R.; Wang, Jie; Han, Hai-Hao; Reeksting, Shaun B.; Sedgwick, Adam C.; He, Xiao-Peng; Bull, Steven D.; James, Tony D.
• Is Part Of: RSC advances. Volume 10:Issue 23(2020)
• Page Start: 13496
• Page End: 13499
• Publication Date: 2020-04-03
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/d0ra02234a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : A coumarin-based novel 'AND' logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO − and biological thiols. Abstract : A coumarin-based novel 'AND' logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO − and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO − analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement.