But-3-ene-1, 3-disulfonyl difluoride (BDF): a highly selective SuFEx clickable hub for the quick assembly of sultam-containing aliphatic sulfonyl fluorides. Issue 58 (16th June 2020)

• Record Type: Journal Article
• Authors: Li, Chen; Zheng, Yujie; Rakesh, K. P.; Qin, Hua-Li
• Is Part Of: Chemical communications. Volume 56:Issue 58(2020)
• Page Start: 8075
• Page End: 8078
• Publication Date: 2020-06-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc03248d
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A versatile SuFEx clickable hub, but-3-ene-1, 3-disulfonyl difluoride (BDF), was designed for selectively constructing 4-, 5- and 6-membered sultam-containing aliphatic sulfonyl fluorides. Abstract : A versatile selectively addressable SuFEx click chemistry hub, but-3-ene-1, 3-disulfonyl difluoride (BDF) was designed and synthesized through head-to-tail dimerization of ethenesulfonyl fluoride (ESF). BDF possesses three active sites to selectively participate in the construction of 4-membered, 5-membered and 6-membered cyclic sulfonamide (sultams) bearing aliphatic sulfonyl fluoride moieties for further manipulations in a fast, efficient and practical manner.