Vitamin Deficiency After Bariatric Surgery and Pregnancy Outcomes [39D]. (May 2020)

• Record Type: Journal Article
• Authors: Harrison, Rachel K.; Braun, Emilie; Semons-Booker, Kia; Lak, Kathleen; Cruz, Meredith; Wlodarczyk, Katarzyna
• Is Part Of: Obstetrics and gynecology. Volume 135(2020)Supplement 1
• Publication Date: 2020-05
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; 618
• DOI: 10.1097/01.AOG.0000663588.17318.13
• Languages: English
• ISSNs: 0029-7844

Abstract

Abstract : INTRODUCTION: Women after bariatric surgery are frequently vitamin deficient. We sought to identify how vitamin deficiencies impact pregnancy outcomes in women with a history of bariatric surgery. METHODS: IRB approval was obtained. Clinical, demographic, and pregnancy information was collected on 158 women with a prior bariatric surgical procedure. Pregnancies were stratified by presence or absence of vitamin deficiency as per their medical record. Maternal and neonatal outcomes were analyzed via univariable and multivariable analyses. RESULTS: Among 158 women who met inclusion criteria, 102 (64.6%) were identified as vitamin deficient. There was no difference in maternal age, race/ethnicity, nulliparity, or pre-bariatric surgery weight when comparing women with and without vitamin deficiency. Vitamin deficient women had lower early pregnancy body mass index (BMI) (34.2±7.4 vs 37.0±8.0 kg/m 2, P =.033), had a history of primarily malabsorptive procedure (86.7% vs 58.9%, P =.001), took supplements plus prenatal vitamins (85.3% vs 57.5%, P =.001), and had anemia at the time of delivery (59.4% vs 38.2%, P =.012). In univariable analysis, there were no differences in rates of preterm delivery, cesarean delivery, gestational diabetes, pregnancy-related hypertension, a composite maternal outcome, birth weight, large-for-gestational age, small-for-gestational age, or a composite neonatal outcome. These findings persisted in multivariable analysis after controlling for confounding factors. CONCLUSION: Pregnant women with vitamin deficiency after bariatric surgery were more likely to have undergone a primarily malabsorptive procedure, had lower BMI in pregnancy, and had higher rates of anemia at the time of delivery. They otherwise did not have worse maternal or neonatal outcomes compared to women without a vitamin deficiency.