Iridium-catalyzed enantioselective reductive amination of aromatic ketones. Issue 16 (6th August 2020) - Liu, Ruixia
Abstract : A highly efficient catalytic system of direct asymmetric reductive amination of aromatic ketones. Abstract : A highly efficient direct asymmetric reductive amination of aromatic ketones catalyzed by an iridium complex of Josiphos-type binaphane ligands was described. This concise and practical method provided chiral amines in high yields and enantioselectivities (up to 99% ee).