A directing group-assisted ruthenium-catalyzed approach to access meta-nitrated phenols. Issue 52 (27th May 2020)

• Record Type: Journal Article
• Authors: Sasmal, Sheuli; Sinha, Soumya Kumar; Lahiri, Goutam Kumar; Maiti, Debabrata
• Is Part Of: Chemical communications. Volume 56:Issue 52(2020)
• Page Start: 7100
• Page End: 7103
• Publication Date: 2020-05-27
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc02851g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : meta -Selective C–H nitration of phenol derivatives was developed using a Ru-catalyzed σ-activation strategy. Cu(NO3 )2 ·3H2 O was employed as the nitrating source, whereas Ru3 (CO)12 was found to be the most suitable metal catalyst for the protocol. Abstract : meta -Selective C–H nitration of phenol derivatives was developed using a Ru-catalyzed σ-activation strategy. Cu(NO3 )2 ·3H2 O was employed as the nitrating source, whereas Ru3 (CO)12 was found to be the most suitable metal catalyst for the protocol. Mechanistic studies suggested involvement of an ortho -CAr –H metal intermediate, which promoted meta -electrophilic aromatic substitution and silver-assisted free-radical pathway.