The construction of fluorophoric thiazolo-[2, 3-b]quinazolinone derivatives: a multicomponent domino synthetic approach. Issue 26 (17th April 2020) - Mohanta, Prajna Parimita
Abstract : A library of unique fluorophoric thiazolo[2, 3- b ]quinazolinones were synthesized under acid catalyzed one pot microwave irradiation technique. Abstract : Acid-mediated one-pot domino reactions of substituted 2-amino thiazoles, substituted benzaldehydes and cyclic diketones have been developed for the synthesis of novel and architecturally unique thiazolo[2, 3- b ]quinazolinone derivatives under microwave irradiation. In this protocol, a series of thiazolo[2, 3- b ]quinazolinone derivatives have been synthesized and the excellent fluorescence behaviors of some of the molecules have been reported based on the incorporation of different electron-donating and electron-withdrawing substituents on the aryl moieties of the target molecules.