Cu-Catalyzed three-component coupling reactions using nitriles, 1, 3-dienes and silylboranes. Issue 34 (9th April 2020) - Matsuda, Yuki
Abstract : Novel Cu-catalyzed three-component coupling reactions using nitriles, 1, 3-dienes and silylboranes have been achieved. The desired reactions proceed at room temperature and yield β, γ-unsaturated ketones. Abstract : This paper reports novel Cu-catalyzed three-component coupling reactions using nitriles, 1, 3-dienes and silylboranes. The desired reactions proceed at room temperature and yield β, γ-unsaturated ketones with a (dimethylphenylsilyl)methyl moiety at the α-position. Diverse nitriles participate in the reaction and the corresponding products were obtained in good to high yields with high regioselectivity.