3D hollow-out TiO2 nanowire cluster/GOx as an ultrasensitive photoelectrochemical glucose biosensor. Issue 11 (27th February 2020)

• Record Type: Journal Article
• Authors: Yang, Wenke; Wang, Xiaohong; Hao, Wanjun; Wu, Qiang; Peng, Juan; Tu, Jinchun; Cao, Yang
• Is Part Of: Journal of materials chemistry. Volume 8:Issue 11(2020)
• Page Start: 2363
• Page End: 2370
• Publication Date: 2020-02-27
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/d0tb00082e
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : A reticulate TiO2 nanowire cluster electrode demonstrated higher sensitivity performance due to enhanced diffusion effect and more number of active sites. Abstract : Ultra-high sensitivity is difficult to achieve using conventional enzymatic glucose biosensors due to the lack of exposed active sites and steric-hinderance effects. Thus, in the present study, we report a photoelectrochemical (PEC) enzymatic glucose biosensor based on 3-dimensional (3D) hollow-out titanium dioxide (TiO2 ) nanowire cluster (NWc)/glucose oxidase (GOx), providing more number of exposed active sites, thus constructing a sensor with a higher affinity toward glucose reaction. Excellent performance with an ultra-high sensitivity of 58.9 μA mM −1 cm −2 and 0–2 mM linear range with a determination limit of 8.7 μM was obtained for the detection of glucose. This study might provide a new approach to expose active sites efficiently for remarkable photoelectrochemical performances.